Search details
1.
Hydrogen tunneling links protein dynamics to enzyme catalysis.
Annu Rev Biochem
; 82: 471-96, 2013.
Article
in English
| MEDLINE | ID: mdl-23746260
2.
Evolution of Optimized Hydride Transfer Reaction and Overall Enzyme Turnover in Human Dihydrofolate Reductase.
Biochemistry
; 60(50): 3822-3828, 2021 12 21.
Article
in English
| MEDLINE | ID: mdl-34875176
3.
Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry
; 60(16): 1243-1247, 2021 04 27.
Article
in English
| MEDLINE | ID: mdl-33829766
4.
Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools.
Proc Natl Acad Sci U S A
; 115(41): 10311-10314, 2018 10 09.
Article
in English
| MEDLINE | ID: mdl-30249644
5.
Rigid Double-Stranded DNA Linkers for Single Molecule Enzyme-Drug Interaction Measurements Using Molecular Recognition Force Spectroscopy.
Langmuir
; 36(15): 4174-4183, 2020 04 21.
Article
in English
| MEDLINE | ID: mdl-32233509
6.
Evolution Conserves the Network of Coupled Residues in Dihydrofolate Reductase.
Biochemistry
; 58(37): 3861-3868, 2019 09 17.
Article
in English
| MEDLINE | ID: mdl-31423766
7.
The role of the Met20 loop in the hydride transfer in Escherichia coli dihydrofolate reductase.
J Biol Chem
; 292(34): 14229-14239, 2017 08 25.
Article
in English
| MEDLINE | ID: mdl-28620051
8.
Evolutionary Effects on Bound Substrate p Ka in Dihydrofolate Reductase.
J Am Chem Soc
; 140(48): 16650-16660, 2018 12 05.
Article
in English
| MEDLINE | ID: mdl-30398861
9.
Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate.
Bioorg Med Chem
; 26(9): 2365-2371, 2018 05 15.
Article
in English
| MEDLINE | ID: mdl-29606487
10.
Protein Mass Effects on Formate Dehydrogenase.
J Am Chem Soc
; 139(48): 17405-17413, 2017 12 06.
Article
in English
| MEDLINE | ID: mdl-29083897
11.
Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier.
Arch Biochem Biophys
; 632: 11-19, 2017 10 15.
Article
in English
| MEDLINE | ID: mdl-28821425
12.
Escherichia coli dihydrofolate reductase catalyzed proton and hydride transfers: temporal order and the roles of Asp27 and Tyr100.
Proc Natl Acad Sci U S A
; 111(51): 18231-6, 2014 Dec 23.
Article
in English
| MEDLINE | ID: mdl-25453098
13.
The Effect of Protein Mass Modulation on Human Dihydrofolate Reductase.
Biochemistry
; 55(7): 1100-6, 2016 Feb 23.
Article
in English
| MEDLINE | ID: mdl-26813442
14.
Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.
Biochemistry
; 55(19): 2760-71, 2016 05 17.
Article
in English
| MEDLINE | ID: mdl-27100912
15.
Noncovalent Intermediate of Thymidylate Synthase: Fact or Fiction?
J Am Chem Soc
; 138(26): 8056-9, 2016 07 06.
Article
in English
| MEDLINE | ID: mdl-27327197
16.
Role of dynamics in enzyme catalysis: substantial versus semantic controversies.
Acc Chem Res
; 48(2): 466-73, 2015 Feb 17.
Article
in English
| MEDLINE | ID: mdl-25539442
17.
Flavin-Dependent Thymidylate Synthase as a New Antibiotic Target.
Molecules
; 21(5)2016 May 20.
Article
in English
| MEDLINE | ID: mdl-27213314
18.
Targeting the de novo biosynthesis of thymidylate for the development of a PET probe for pancreatic cancer imaging.
Biochemistry
; 54(5): 1287-93, 2015 Feb 10.
Article
in English
| MEDLINE | ID: mdl-25581782
19.
Evolutionary aspects of enzyme dynamics.
J Biol Chem
; 289(44): 30205-30212, 2014 Oct 31.
Article
in English
| MEDLINE | ID: mdl-25210031
20.
Determination of concentration and activity of immobilized enzymes.
Anal Biochem
; 484: 169-72, 2015 Sep 01.
Article
in English
| MEDLINE | ID: mdl-25707319